Gut-Brain-Adrenal Axis

Gut-Brain-Adrenal Axis

The Gut-Brain Axis

You may have heard of the Gut-Brain Axis. It’s been a hot topic among nutritional therapists and other health professionals for a while now.

What’s more, we’re learning more and more about the impact of their relationship all the time:

  • How the balance of your gut bacteria can affect your mood, mental health and even addictive behaviour.
  • How the nervous system in your gut not only receives information from your brain, but largely sends instructions back up to your brain that influence its activity – primarily via the vagus nerve
  • How stress and emotions can trigger muscle contractions, inflammation and digestive secretions in your stomach and intestines.
  • How the resulting inflammation and bacterial imbalance affects your immune responses throughout your body

There’s a two-way relationship between your gut and your brain/central nervous system that just can’t be ignored.

Gut-Brain Axis

Vagus Nerve

I would now like to introduce you to a third and very important member of the team: your adrenals.

Your adrenals

Your adrenals are part of your hormonal system, the part which sounds out the sirens in cases of red alert. They can help convert you, in an instant, from a rational being calmly going about their day, digesting your last meal, weighing up the pros and cons of going to the pub tonight – into a wildcat, crouched and ready to spring into action, be it to fight tooth and claw or sprint away. Or, perhaps more often, into a rabbit caught in the headlights, frozen into inactivity. (This too has its benefits, as freezing can sometimes be your safest response, and at the very least, numbs you at the time of impact.)

WildcatWhether wildcat or rabbit, in that moment you have downgraded all non-essential activity, including digestion and intellectual thought. Instead, your resources are focused on your heart and external muscles (either for running, fighting or freezing), and your brain activity has turned reptilian. The new, evolved frontal lobe of your brain, where you think things through, is too slow for dangerous situations, while your amygdala, the oldest part of your brain, can react instantly to keep you safe.

Having reacted, through fight or flight or freezing, if you are now in a safe place again, you may find yourself shaking, laughing or sobbing. This is your basic reset.

Pause for a second and ask yourself: how much resetting have you been doing lately? Or are you still a little frozen, or pumped up with adrenalin?


The Gut-Brain-Adrenal Triangle*

So how does this fit into your gut-brain axis? Well, for a start, there’s a direct influence there on whether your brain and nerve activity are being dominated by your calm, rational frontal lobe or your fear-based amygdala. And we know so much already about how your nervous system affects your gut. Your gut is so well connected to your nervous system by so many nerve endings and neurotransmitters that it’s even known as the enteric nervous system, or sometimes as your second brain.

In addition, if you’re stuck in a long term fight/fight/freeze response, then you usually end up over producing cortisol. Cortisol is another adrenal hormone, which in an ideal world calms down inflammation. However, when it’s continually being pumped out, your body stops listening to it. (Just like we can all stop listening to a nag droning on…)

Which means you are now no good at calming down inflammation. Which means that any inflammation in your digestive system will have a hard time cooling off.

Now remember that your digestive system has been downgraded, so you aren’t breaking foods down efficiently either. Which means that some of them may be causing irritation and inflammation in your gut.

And while we’re on the subject, they’re may be a number of foods that are in your regular diet that may be agitating your gut already. Or maybe a lack of hydration, or a lack of certain nutrients it needs to keep your gut tissue healthy.

Your body may be getting quite stressed about all this, which can additionally set your nerves on edge, and keep your adrenals fired up. Plus your adrenals will be sending out cortisol to quench the inflammation in your gut. Only this may have been going on so long now that your gut isn’t listening any more.

And there you have it in the simplest terms. The Gut-Brain-Adrenal Axis, aka The Gut-Brian Adrenal Triangle*.



It’s not an isolated little unit, however. Activating this triangle can impact on your physical and mental health in countless ways. It’s becoming increasingly acknowledged that long term inflammation underpins all chronic illness, including heart disease, diabetes, depression, cancer, asthma and rheumatoid arthritis.

Like the Bermuda Triangle, it’s easy to get lost in here. The good news is, you can find your way out again, with the help of a few nutritional and lifestyle changes. I’ve found that this triangle sits naturally at theNutrition Workshop with Kirsten heart of all the work I do as a nutritional therapist, and so it’s the most useful thing I can share with you right now.

To find out more and learn practical ways of keeping your Gut-Brain-Adrenal axis* in balance, come to our Bloom Day Retreats and/or our Bloom Summer Retreat. I (Kirsten) will be explaining this in more depth and talking about how to bring about change, and Hayley will take it all to the kitchen with you.


*The Gut-Brain-Adrenal Axis and The Gut-Brain-Adrenal Triangle are both terms Kirsten Chick uses to help describe their relationship and impact on overall health and wellbeing. Her forthcoming book aims to explain this in more detail.